News

There is so much happening across Glasgow and the West of Scotland and our news portal will allow us to share it with you.

Blood test could help to accelerate brain cancer diagnosis

Brain

A blood test which could help to accelerate the diagnosis of brain cancer has been developed in research led at the University of Strathclyde.

The patented technology uses infrared light to produce a 'bio-signature' of a blood sample and applies artificial intelligence to check for the signs of cancer.

This research is being commercialised by ClinSpec Diagnostics Limited, an award-winning company spun out from the university in February 2019.

The work has now been published in the journal Nature Communications, and also involved clinicians at the Western General Hospital in Edinburgh, the University of Liverpool and the Walton NHS Foundation Trust in Liverpool.

Dr Matthew J. Baker, Reader in Strathclyde’s Department of Pure and Applied Chemistry and Chief Scientific Officer with ClinSpec Diagnostics, led the study.

He said: “This is the first publication of data from our clinical feasibility study and it is the first demonstration that our blood test works in the clinic. Earlier detection of brain tumours in the diagnostic pathway brings the potential to significantly improve patient quality of life and survival, whilst also providing savings to the health services.”

Dr Holly Butler, Research and Development Director with ClinSpec Diagnostics, said: “The results presented are the beginning of a clinical roadmap of studies, that aim to bring the technology through regulatory approval, and ultimately to provide patients with rapid access to diagnosis and treatment.”

Dr Paul Brennan, Senior Clinical Lecturer and Consultant Neurosurgeon at the University of Edinburgh, a partner in the study, said: “Diagnosing brain tumours is difficult, leading to delays and frustration for lots of patients.

"The problem is that symptoms of brain tumour are quite non-specific, such as headache, or memory problems. It can be difficult for doctors to tell which people are most likely to have a brain tumour. 

“With this new test, we have shown that we can help doctors quickly identify which patients with these non-specific symptoms should be prioritised for urgent brain imaging. This means a more rapid diagnosis for people with a brain tumour, and quicker access to treatment.”

The Brain Tumour Charity ambassador Hayley Smith, whose husband Matthew is currently living with a glioblastoma brain tumour is backing this research.

They learned in July 2016, three weeks after Matthew’s surgery, that his tumour was a grade 4 glioblastoma.

West-Lothian-based Hayley said: "We urgently need to find new treatments and ultimately a cure as more and more people are being diagnosed with this devastating disease.

"It is very encouraging to hear that this blood test can lead to a quicker diagnosis for brain cancer.

"Matthew's doctors believe that his brain tumour was slowly growing for around 14 years but only started presenting symptoms that could be linked to a brain tumour around six weeks before he ended up in A and E following a seizure.

"Initially these symptoms had been misdiagnosed as a migraine - had this new test been available it might have been spotted earlier.

"Scotland now has research teams from all over the world and all are experts in their fields. It's so promising to know that we have the best of the best looking into quicker diagnosis and new treatments.

"This kind of test will be vital to patients, helping people to get the correct diagnosis quicker which ultimately will help people to get the urgent medical care that they need."

Patients with brain cancer frequently present with non-specific symptoms and the final cancer diagnosis can be time-consuming.

The researchers have analysed samples from a prospective cohort of 104 patients, they found that the blood test could distinguish patients with brain cancer from healthy individuals correctly 87 per cent of the time.

These findings suggest that this approach may be useful to doctors in helping to prioritise patients needing brain scans in order to diagnose tumours. While the proposed system does not offer an absolute diagnosis, it could play a significant role in the diagnostic process as a triage tool.

 

Links

University of Strathclyde


No Comments...


Add a comment

01 07 07 01 Audio Captcha
Add Comment
 

 

What’s happening

This is a living, breathing website with regular updates on news, blogs and events. It’s the place to come back to again and again if you want to know what’s happening in the science and technology world in Glasgow and the West of Scotland.

Subscribe to keep up to date on our latest news, blog posts and events.

News

   

Scientists make vampire bats ‘glow’ to simulate vaccine spread

Scientists have used ‘glowing’ fluorescent gel to estimate the potential effectiveness of spread...

Read more...


Early bird registration open for IBioIC annual conference

IBioIC's 6th annual conference will take place in Glasgow on February 5 and 6, 2020. ...

Read more...


Landmark drug trial could revolutionise treatment for type 1 diabetes

University of Glasgow researchers are eagerly anticipating the initiation of a pioneering new global...

Read more...

Blog

   

Game of Drones: A Song of Boats and LiDAR

Drones in the sky, drones in the sea, drones on land. Could drones be doing more for you? At Art of ...

Read more...


Grounds to create global change

To mark International Zero Waste Week Scott Kennedy, co-founder of Revive Eco and member of Industri...

Read more...


Learning to fuel the growth of a more sustainable world

Rachel Clark from the Industrial Biotechnology Innovation Centre (IBioIC) encourages students into s...

Read more...

Events

   

Data Analytics for Manufacturing

An informative workshop on data analysis....

Read more...


Arika -- Episode 10: A Means Without End

Complex ways of understanding our complex times. Maths & Poetics. Gesture & Physics. Collect...

Read more...


Graphic Design Festival Scotland

The Graphic Design Festival Scotland aims to inspire young designers through active engagement, all ...

Read more...

previous post next post